Lossofheterozygosity相关论文
Analysis of loss of heterozygosity in an anencephalus fetus using high-resolution array-based compar
Objective To analyze loss of heterozygosity (LOH) in a fetus affected anencephalus.Methods A routine G-banding karyotype......
Alterations of chromosome 3p in 24 cases of gastrinomas and their correlations with clinicopathologi
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High frequency loss of heterozygosity on the long arms of chromosomes 13 and 14 in nasopharyngeal ca
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A genome-wide allelotype study of primary and corresponding recurrent glioblastoma multiforme in one
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Two closely neighboring hepatocellular carcinomas mimicking intrahepatic metastasis are confirmed as
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Loss of heterozygosity on chromosome 22 in sporadic schwannoma and its relation to the proliferation
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Accurate detection of genomic aberrations in impure and aneuploid tumor samples using whole-genome s
Background: Various aberrations such as amplification, deletion and translocation of segmental regions are common fe......
多形性腺瘤（ PA）是唾液腺最常见的上皮性肿瘤，具有交界性肿瘤的特性，肿瘤病程长或多次复发可恶变为恶性PA。 PA的恶变过程是多基因、多......
目的 探讨二种儿童胚胎性肿瘤--肾母细胞瘤和神经母细胞瘤中微卫星不稳定性(microsatellite instability,MSI)与杂合性缺失(loss o......
Genetic alterations and reduced expression of tumor suppressor p33ING1b in human exocrine pancreatic
AIM: To detect the expression of p33ING1b protein and the change of p33ING1b gene in pancreatic carcinoma and to evaluat......
Loss of heterozygosity on chromosome 10q22-10q23 and 22q 11.2-22q12.1 and p53 gene in primary hepato
AIM: To analyze loss of heterozygosity (LOH) and homozygous deletion on p53 gene (exon2-3, 4 and 11), chromosome10q22-10......
Neoplastic progression is generally characterized by the accumulation of multiple genetic alterations including loss of ......
Loss of heterozygosity on 10q23.3 and mutation of tumor suppressor gene PTEN in gastric cancer and p
AIM: To investigate the loss of heterozygosity (LOH) and mutation of tumor suppressor gene PTEN in gastric cancer and pr......
AIM: To investigate loss of heterozygosity (LOH) and microsatellite instability (MSI) on the chromosomal region 1p36-pte......
Genetic instability of BRCA1 gene at locus D17S855 is related to clinicopathological behaviors of ga
AIM: To investigate genetic instability of gene BRCA1 at locus D17S855, and their relationship with clinicopathological ......
Rationales for expression and altered expression of apoptotic protease activating factor-1 gene in g
AIM: To elucidate the relationship between apoptotic protease activating factor-1 (Apaf-1) gene and gastric cancer.METHO......
Clinical significance of loss of heterozygosity for M6P/IGF2R in patients with primary hepatocellula
AIM:To investigate the relationship between loss of heterozygosity (LOH) for mannose 6-phosphate/insulin-like growth fac......
LOH analysis of genes around D4S2964 identifies ARD1B as a prognostic predictor of hepatocellular ca
AIM: To investigate genes around the locus D4S2964 affected by loss of heterozygosity (LOH) and their clinical implicati......
CHROMOSOME 3 MAY HARBOR MULTIPLE TUMOR SUPPRESSOR GENES ASSOCIATED WITH PRIMARY GLIOBLASTOMA MULTIFO
Objective: To investigate whether deletion of chromosome 3 is involved in the carcinogenesis of primary glioblastoma mul......
目的 探讨甲状腺肿瘤中3号染色体短臂(3p)杂合性缺失(LOH)状态及其临床意义.方法 收集74例甲状腺肿瘤标本,包括20例甲状腺腺瘤(FA)......
目的 探讨抑癌基因RASSF1A微卫星变异在宫颈癌发生发展中的作用及其与HPV感染的关系.方法 选择RASSF1A基因的两个微卫星多态标记位......
目的 研究散发性结直肠癌5号染色体的杂合性缺失,寻找新的结直肠癌抑癌基因.方法 取83例结直肠癌患者的肿瘤和正常组织,先后应用分......
目的评价染色体14q的(杂合性)丢失是否与原发性多形性胶质母细胞瘤的发生发展有关,并确定14q上可能存在的共同杂合性丢失区域.方法......
Objective: To explore the loss of heterozygosity(LOH) on chromosome 6q in ovarian cancer, and localize a minimum area in......
目的 探讨肿瘤转移抑制基因KAI1与胰腺癌转移及预后的相关性,并进一步研究此相关性与其等位基因杂合性缺失(LOH)的关系.方法 收集......
目的 研究少突胶质细胞肿瘤分子遗传学改变和肿瘤部位的相关性.方法 回顾性地研究了105例胶质瘤.根据影像学资料记录每例肿瘤的部......
背景与目的:人乳头瘤病毒的感染以及细胞内的遗传性改变是宫颈癌的主要病因.本研究拟分析人宫颈癌组织部分染色体位点遗传不稳定性......
In order to assess the role of the changes of DCC and APC/MCC genes in the development and progtession of gastric cancer......
Objective. To investigate the BRCA1 gene in hereditary breast and ovarian cancer, early-onset breast cancer and sporadic......
